yezG [2020-03-05 09:59:09]

antitoxin

locus: BSU_06811

pI: 4.00

mw: 18.00 kDa

protein length: 151 aa

gene length: 456 bp

function: inhibition of the cytotoxic activity of [protein|655C07294D3A04763049D6701A7296BB4AF8E6B9|YeeF]

product: antitoxin

essential: yes

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.2|Type 2 TA systems]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.18|Toxins, antitoxins and immunity against toxins/ based on similarity]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

Gene

Coordinates: 747,079 747,534

Phenotypes of a mutant

• essential [Pubmed|28189581]
• a [gene|655C07294D3A04763049D6701A7296BB4AF8E6B9|yeeF]-[gene|search|yezG ]double mutant is viable [Pubmed|28189581]

The protein

Structure

• [PDB|2IA1] (from B. halodurans, 27% identity)

Expression and Regulation

Operons

• genes: [gene|9202D58FAC1B7B9CF693D537A12C683A3573B17E|yezG]
  description: [pubmed|22383849]

• genes: [gene|655C07294D3A04763049D6701A7296BB4AF8E6B9|yeeF]-[gene|9202D58FAC1B7B9CF693D537A12C683A3573B17E|yezG]
  description: [pubmed|22383849]

References

• 22200572,28189581